Crushing in the production process of rotary tablet press

Release time:

2021-09-23 10:07

Source:

When shaking or placing the tablet, the cracked waist is called the lumbar♦ fissure, and the cracked top is called the lid. The lumbar fissure and∑ the top cap are collectively referred to as the lung lobe. Nowrotary tablet pressThe cracking phenomenon during tabletting will be shared with everyone.

1. If the pressure is too high, the pressure of the particles will increa'se, and the swelling degree will also increase. The bonding force of the adhesive cannot‌ inhibit its expansion, so cracks will occur.

2. The upper punch and die hole do not meet the requirements. The÷ die used for a long time gradually wears out, resulting in incorrect arrangement of∑ the upper punch and die holes. The upper punch has obvious inwa‍rd curl, and uneven pressure will cause excessive comλpression of the film, causing the die ring to become apical or deformed.

3. The speed of the tablet press is too fast and the tabletting time is too short, whic±h makes the tabletting suddenly compress and recompress, and then suddenly expand and ₹crack. Therefore, the pre-compression time increases.

4. Improper selection of binder, too little binder during graγnulation, insufficient viscosity after drying, too much €fine powder, and too hard dry particles, which will cause surface disintegration and pitting difficulties, and b≠inder should be added appropriately; if there is too much fine powder, Some can≈ be screened out; if the particles are too hard, please reprocess, regranulate, and add disintegrβant.

5. The particles do not meet the requirements, the texture is loo∞se, and too much fine powder causes cracks. The improved method should₽ adjust the concentration and dosage of the binder, and improve ↑the granulation method to overcome it.

6. The particles are too dry, and the drug containin♦g crystal water is lost too much, resulting in fragmentation. This solution is the same as the movie.

7. Some crystalline drugs are not completely crushed. This drug can be fully crushed and then ‍made into particles.

8. The room temperature and humidity of the tablet pγress are low, which may cause fragments, especially drugs with poor viscosityα. Adjust the temperature and humidity system accordingly.

Key words:

Laboratory Equipment

Packaging Equipment

pharmaceutical equipment

Pharmaceutical machinery

Analysis of the structure and scope of application of t✔ablet press equipment

4 structures of rotary tablet press

The working principle of the catalyst tablet press is mainly based on powder compaction technology. By the action of high press§ure, the catalyst raw material powder is filled into a "mold, and a solid tablet having a certain shape and hardness is formed through a pressing p rocess. In this process, the tablet press adjusts paramet♠ers such as pressure, speed and time through a precise control system to e§nsure the uniformity and stability of the pressed catalyst tablets.

Catalyst tablet press efficient production weapon for che±mical industry

Catalyst tablet press, as an important equipment in the field of modern chemical industry, is specially used to compress catalyst raw material powder under high pressure to fγorm catalyst tablets in solid shape. This equipment not only improves the prγoduction efficiency of the catalyst, but also has a ↕profound impact on the production efficiency and environmental protection of ≥the entire chemical industry.

Three-layer tablet press key equipment for pharmaceutical and™ chemical industry

The three-layer tablet press is an efficient and versatile pharmaceutical and c‍hemical production equipment that can compress powdered materials into tablets or granules ≈of various shapes and specifications. This kind of equipment is widely used in pharmaceuticaσl, chemical, food and other industries, and is an indispensable part o₽f the production process.

Three-layer tablet press assistant in the pharmaceutica↑l and chemical industry

The three-layer tablet press is an efficient and versatile pharmaceutical and chemi₽cal production equipment that can compress powdered materials← into tablets or granules of various shapes and specificatiβons. The equipment in the pharmaceutical, chemical, food and other in<dustries have a wide range of applications, become an indispen¥sable tool in these industries.

Three-layer tablet press Production weapon for pharmaceutical and chemical industry

The three-layer tablet press is a highly efficient and ver↓satile pharmaceutical and chemical production equipment that can compress powde∑red materials into tablets or granules of various shapes and specifications. Thi∏s kind of equipment is widely used in pharmaceutical, cεhemical, food and other industries, and has become an important too l to improve production efficiency and ensure product quality.

Three-layer tablet press high-performance powder material pressing equ$ipment

The three-layer tablet press is mainly composed of upper and lower tabl≥et wheels, intermediate conveyor belts, and related metering, feeding and driving s±ystems. During operation, the material is fed through ♦an intermediate conveyor belt to be compressed betwee↑n two tabletting wheels to form tablets or granules. The equipment adopt♣s modular design, which is easy to install, debug and maintain. At δthe same time, it is equipped with advanced PLC programmable control system to realize autom©atic production.